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Transporting Therapeutics into The Brain

biOasis Technologies Inc. has developed and is now commercializing a ground-breaking platform for the delivery of therapeutic compounds across the blood-brain barrier and into the Central Nervous System for the treatment of neurological diseases, including, but not limited to, brain cancers, neurodegenerative and metabolic diseases. With the ability to transport therapeutics of almost any type and size across the blood-brain barrier, the Transcend Platform is now available to be licensed by biotechnology and pharmaceutical companies for the advancement of their neurotherapeutic programs.

 

The Transcend Platform

The Transcend Platform consists of a diverse suite of peptide carriers and linkers that together provide transport solutions for a host of CNS therapeutics including monoclonal antibodies, enzymes, small molecules and various types of gene therapies.

Designed to deliver high concentrations of therapeutics into the CNS with minimal dosing requirements and with no disruption of the blood-brain barrier, The Transcend Platform is based on Receptor Mediated Transcytosis, nature’s own method of carrying compounds into the brain. The Transcend Platform has achieved an exceptionally high success rate in the transport of dozens of compounds across the BBB in both in vitro and in vivo studies at over twenty third-party institutions and corporations. The studies illustrate that the Transcend Peptide does not materially affect either the half-life or efficacy of the transported therapeutics. Data from many of these studies are available for review by pharmaceutical and biotech corporations and institutions.

Licensing Opportunities

biOasis has developed flexible licensing models that allow pharmaceutical companies and biotechs to advance and commercialize their neurotherapeutic pipelines. The Transcend Platform’s comprehensive patent structure provides licensees with exceptional protection of their intellectual property and with the opportunity to further protect fusion proteins and conjugates developed within the terms of their biOasis Transcend Platform licenses.

Recent News

biOasis Appoints Doug Williams, MBA, Executive Vice President, Chief Business Officer

Monday, August 21, 2017|Comments Off on biOasis Appoints Doug Williams, MBA, Executive Vice President, Chief Business Officer

Williams bring significant experience in working with both large, multinational pharmaceutical companies & start-up biotechnology alliances

August 21, 2017, Vancouver, BC

VANCOUVER, BC, BIOASIS TECHNOLOGIES INC. (OTCQB:BIOAF; TSX.V:BTI) welcomes Doug Williams, MBA, as executive vice president, chief business officer, effective immediately. Williams will report to Dr. Mark Day, president and chief executive officer of biOasis. In this newly created position, Williams will provide leadership and execute on the corporate development strategy that will maximize benefits for strategic partners and shareholders. Williams will be responsible for leading corporate and business development, as well as the alliance management efforts at biOasis.

“We are delighted to welcome Doug Williams to our senior management team at biOasis. I know he will bring value as a business development leader and well-respected and strategic alliance professional,” said Dr. Day. “Doug will play a critical role in advancing our partnering strategy and create value through the prosecution of licensing opportunities for our proprietary blood-brain barrier drug delivery platform.”

Williams has more than 20 years of experience in the pharmaceutical and healthcare industries and has successfully led cross-functional, global alliances teams across multiple organizations.  His alliance and partnering experience includes a broad set of partners including large, multinational pharmaceutical companies, as well as start-up biotechnology companies, which included global alliances with Shionogi, Exicure, AbbVie, Mylan and Takeda, among others.

Williams has been recognized as an industry leader who has presented, participated as a panelist, and moderated multiple industry partnering programs at industry events.

“Doug has a broad set of experiences having worked in leadership roles at healthcare technology start-ups, pharmaceutical and biotechnology companies. His diverse experience base will help propel our global partnering efforts,” said Rob Hutchison, founder and chairman of the board of directors. “Doug will be a great addition to the biOasis leadership team.”

Williams most recently came from Purdue Pharma L.P where he worked on strategic alliances and business development projects related to clinical and pre-clinical programs. Prior to Purdue, Williams built his own successful consulting business working with start-up healthcare technology companies.  Doug’s experience includes commercial sales, sales management, alliance management and business development.  He has also held various positions of increasing responsibility at Pfizer, Johnson & Johnson, Elan, Sepracor and Kadmon over his 20 year career.

“I am eager to work with Mark on shaping the business strategy for biOasis as we continue to advance our proprietary blood-brain barrier technology platform,” said Williams. “I want to thank Rob and Mark for this opportunity. I look forward to sharing the biOasis story with new potential collaborators and leading the licensing and partnering efforts on behalf of the company and our shareholders.”

About biOasis

biOasis Technologies Inc. is a biopharmaceutical company focused on overcoming the limitations of therapeutic drug delivery across the blood-brain barrier (BBB). The delivery of therapeutics across the BBB represents the single greatest challenge in treating neurological disorders. The company is developing and commercializing a proprietary brain delivery technology to address unmet medical needs in the treatment of central nervous system diseases and disorders. The company maintains headquarters in Vancouver, Canada with offices in Connecticut, United States. biOasis trades on the OTCQB under the symbol “BIOAF” and on the TSX Venture Exchange under the symbol “BTI.” For more information about the company please visit www.bioasis.ca.

Forward-Looking Statements

Certain statements in this press release contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 or forward-looking information under applicable Canadian securities legislation that may not be based on historical fact, including without limitation statements containing the words “believe,” “may,” “plan,” “will,” “estimate,” “continue,” “anticipate,” “intend,” “expect” and similar expressions. Such forward-looking statements or information involve known and unknown risks, uncertainties and other factors that may cause our actual results, events or developments, or industry results, to be materially different from any future results, events or developments express or implied by such forward-looking statements or information. Such factors include, among others, our stage of development, lack of any product revenues, additional capital requirements, risk associated with the completion of clinical trials and obtaining regulatory approval to market our products, the ability to protect our intellectual property, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing. Specifically, certain risks and uncertainties that could cause such actual events or results expressed or implied by such forward-looking statements and information to differ materially from any future events or results expressed or implied by such statements and information include, but are not limited to, the risks and uncertainties that: products that we develop may not succeed in preclinical or clinical trials, or future products in our targeted corporate objectives; our future operating results are uncertain and likely to fluctuate; we may not be able to raise additional capital; we may not be successful in establishing additional corporate collaborations or licensing arrangements; we may not be able to establish marketing and the costs of launching our products may be greater than anticipated; we have no experience in commercial manufacturing; we may face unknown risks related to intellectual property matters; we face increased competition from pharmaceutical and biotechnology companies; and other factors as described in detail in our filings with the Canadian securities regulatory authorities at www.sedar.com. Given these risks and uncertainties, you are cautioned not to place undue reliance on such forward-looking statements and information, which are qualified in their entirety by this cautionary statement. All forward-looking statements and information made herein are based on our current expectations and we undertake no obligation to revise or update such forward-looking statements and information to reflect subsequent events or circumstances, except as required by law.

On Behalf of the Board of Directors
Dr. Mark Day, President and Chief Executive Officer

“Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.”

 

Company Contacts

Catherine London
Catherine@biasis.ca
+1 917 763 2709

Graeme Dick
info@bioasis.ca
+1 403 561-8989

biOasis Appoints Catherine London, Executive Vice President, Head of Corporate Communications and Investor Relations

Sunday, June 25, 2017|0 Comments

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June 26, 2017, Vancouver, BC

BIOASIS TECHNOLOGIES INC. (OTCQB:BIOAF; TSX.V:BTI) welcomes Catherine London as executive vice president, head of corporate communications and investor relations, effective immediately. London will report to Dr. Mark Day, president and chief executive officer of biOasis. In this newly created position, London will have responsibility for leading all external communications, corporate visibility, brand-building, reputation management, financial communications and investor relations.

“The Board of Directors and I are delighted to welcome Catherine London to our senior management team at biOasis. Having worked with Catherine previously, I know she is a forward-thinking communications leader and collaborative relationship builder,” said Dr. Mark Day. “She will play a critical role in the strategic design and execution of communications and investor relations initiatives to drive business growth. I look forward to working with her again.”

“Catherine brings with her the broad pharmaceutical and biotechnology industry expertise and experience we are looking for to help propel biOasis globally,” said Rob Hutchison, founder and chairman of the board of directors. “She will be an instrumental member of the team.”

London has more than 22 years of experience in the pharmaceutical and healthcare industries and has successfully led large, global teams and strategic plans. London most recently served as the head of corporate communications at Purdue Pharma L.P. Prior to Purdue, London served in director-level roles in corporate and product communications at Alexion Pharmaceuticals, Inc. and Boehringer Ingelheim Pharmaceuticals, Inc. In these roles, her responsibilities included executive, corporate, product and financial communications, government and policy communications and business communications. London has also held senior leadership roles at global consulting firms such as the Chandler Chicco Companies, an inVentiv Health Company, which includes Chamberlain, Chandler Chicco and BioSector2, and at Ruder Finn.

“I believe in Mark’s vision and business strategy for biOasis as well as the promise of the in-house programs and Transcend platform. This is truly an exciting time in the neuroscience field and we have a great story to tell at biOasis,” said London. “I want to thank the board of directors, Rob Hutchison and Mark for this opportunity. I look forward to leading the communications and investor relations on behalf of the company and its shareholders.”

London began her career as a reporter and editor working at print and broadcast outlets in various U.S. markets before taking a turn as a science journal editor and eventually making the transition to public affairs at the American Diabetes Association. London holds a bachelor of arts degree in journalism from Auburn University in Auburn, Ala.

About Transcend
Transcend is biOasis’ proprietary platform for the delivery of therapeutics across the blood-brain barrier to address unmet medical needs in the treatment of metastatic brain cancers as well as neurodegenerative and metabolic diseases. The delivery of therapeutics across the blood-brain barrier represents the single greatest challenge in treating neurological disorders. The ability to effectively and safely transverse the blood-brain barrier with the Transcend peptide carrier, MTfp, offers the opportunity for biOasis to deliver therapeutics into the brain at doses sufficient to have a therapeutic effect.

About biOasis
biOasis Technologies Inc. is a biopharmaceutical company with offices in Canada and the U.S., focused on overcoming the limitations of therapeutic drug delivery across the blood-brain barrier (BBB). The company is developing and commercializing a proprietary brain delivery technology to address unmet medical needs in the treatment of central nervous system disorders. biOasis trades on the OTCQB under the symbol “BIOAF” and on the TSX Venture Exchange under the symbol “BTI.” For more information about the company please visit www.bioasis.ca.

Forward Looking Statements
Certain statements in this press release contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 or forward-looking information under applicable Canadian securities legislation that may not be based on historical fact, including without limitation statements containing the words “believe,” “may,, “plan,” “will,” “estimate,” “continue,” “anticipate,” “intend,” “expect” and similar expressions. Such forward-looking statements or information involve known and unknown risks, uncertainties and other factors that may cause our actual results, events or developments, or industry results, to be materially different from any future results, events or developments express or implied by such forward-looking statements or information. Such factors include, among others, our stage of development, lack of any product revenues, additional capital requirements, risk associated with the completion of clinical trials and obtaining regulatory approval to market our products, the ability to protect our intellectual property, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing. Specifically, certain risks and uncertainties that could cause such actual events or results expressed or implied by such forward-looking statements and information to differ materially from any future events or results expressed or implied by such statements and information include, but are not limited to, the risks and uncertainties that: products that we develop may not succeed in preclinical or clinical trials, or future products in our targeted corporate objectives; our future operating results are uncertain and likely to fluctuate; we may not be able to raise additional capital; we may not be successful in establishing additional corporate collaborations or licensing arrangements; we may not be able to establish marketing and the costs of launching our products may be greater than anticipated; we have no experience in commercial manufacturing; we may face unknown risks related to intellectual property matters; we face increased competition from pharmaceutical and biotechnology companies; and other factors as described in detail in our filings with the Canadian securities regulatory authorities at www.sedar.com. Given these risks and uncertainties, you are cautioned not to place undue reliance on such forward-looking statements and information, which are qualified in their entirety by this cautionary statement. All forward-looking statements and information made herein are based on our current expectations and we undertake no obligation to revise or update such forward- looking statements and information to reflect subsequent events or circumstances, except as required by law.

On Behalf of the Board of Directors
Dr. Mark Day, President and Chief Executive Officer

“Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.”

Company Contact
Graeme Dick
biOasis Technologies Inc.
info@bioasis.ca
1- (403) 561-8989

biOasis Engages FreeMind Group to Access Non-Dilutive Global Funding Opportunities

Thursday, June 15, 2017|0 Comments

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June 15, 2017, Vancouver, BC

BIOASIS TECHNOLOGIES INC. (OTCQB:BIOAF; TSX.V:BTI) announced today it has engaged FreeMind Group to assist the Company pursue non-dilutive funding opportunities globally.

The biOasis Transcend technology has been demonstrated to transport several different drug modalities (e.g., antibodies, enzymes, small molecules) across the blood-brain barrier (BBB) and into the central nervous system (CNS). The value in Transcend is the potential to turn non-brain-penetrant drugs into novel medical entities, to deliver them to the brain and to treat a range of disorders (e.g., oncology, lysosomal disorders and neurodegenerative diseases). Therefore, Transcend has the potential to treat more than one hundred identified brain and other CNS disorders.

Non-dilutive funding is available for many of these disorders from multiple government and private sources. FreeMind Group has the expertise to identify these funding sources and to assist biOasis throughout the funding process, from the preparation and submission of funding applications to pre-award negotiations.

“As we advance our internal programs, it is important to continue to drive new scientific discoveries and understand which diseases the Transcend platform may best serve. To this end, Freemind is an important strategic addition to our armamentarium. Dr. Reinhard Gabathuler, chief scientist, biOasis, will manage this collaboration,” said Dr. Mark Day, chief executive officer.

“FreeMind can play an important dual role for us, both protecting shareholder value and helping biOasis identify potential diseases and translational endpoints of interest,” said Dr. Day. “Much of the work we will conduct fits well within the mandate of many organizations that provide this type of non-dilutive funding. FreeMind has a strong track record and is highly regarded by academia, industry, and the funding organizations. This should provide biOasis with greater opportunities for success in the grant funding process.”

About FreeMind
Established in 1999, FreeMind is the largest consulting group of its kind working with academics and industry alike. FreeMind assists in maximizing potential to receive funding from non-dilutive sources such as the NIH, DOD, NSF, FDA, BARDA, as well as private foundations. FreeMind assists in the guiding of non-dilutive funding efforts from identification of the most suitable opportunity through to submission and subsequent award. FreeMind has garnered its clients over $1.5 billion to date. Awards range from $150,000 to $150million per project.

About Transcend
Transcend is biOasis’ proprietary platform for the delivery of therapeutics across the blood-brain barrier to address unmet medical needs in the treatment of metastatic brain cancers as well as neurodegenerative and metabolic diseases. The delivery of therapeutics across the blood-brain barrier represents the single greatest challenge in treating neurological disorders. The ability to effectively and safely transverse the blood-brain barrier with the Transcend peptide carrier, MTfp, offers the opportunity for biOasis to deliver therapeutics into the brain at doses sufficient to have a therapeutic effect.

About biOasis
biOasis Technologies Inc. is a biopharmaceutical company headquartered in the Vancouver, Canada area, focused on overcoming the limitations of therapeutic drug delivery across the blood-brain barrier (BBB). The company is developing and commercializing a proprietary brain delivery technology to address unmet medical needs in the treatment of central nervous system disorders. biOasis trades on the OTCQB under the symbol “BIOAF” and on the TSX Venture Exchange under the symbol “BTI.” For more information about the company please visit www.bioasis.ca.

Forward Looking Statements
Certain statements in this press release contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 or forward-looking information under applicable Canadian securities legislation that may not be based on historical fact, including without limitation statements containing the words “believe,” “may,” “plan,” “will,” “estimate,” “continue,” “anticipate,” “intend,” “expect” and similar expressions. Such forward-looking statements or information involve known and unknown risks, uncertainties and other factors that may cause our actual results, events or developments, or industry results, to be materially different from any future results, events or developments express or implied by such forward-looking statements or information. Such factors include, among others, our stage of development, lack of any product revenues, additional capital requirements, risk associated with the completion of clinical trials and obtaining regulatory approval to market our products, the ability to protect our intellectual property, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing. Specifically, certain risks and uncertainties that could cause such actual events or results expressed or implied by such forward-looking statements and information to differ materially from any future events or results expressed or implied by such statements and information include, but are not limited to, the risks and uncertainties that: products that we develop may not succeed in preclinical or clinical trials, or future products in our targeted corporate objectives; our future operating results are uncertain and likely to fluctuate; we may not be able to raise additional capital; we may not be successful in establishing additional corporate collaborations or licensing arrangements; we may not be able to establish marketing and the costs of launching our products may be greater than anticipated; we have no experience in commercial manufacturing; we may face unknown risks related to intellectual property matters; we face increased competition from pharmaceutical and biotechnology companies; and other factors as described in detail in our filings with the Canadian securities regulatory authorities at www.sedar.com. Given these risks and uncertainties, you are cautioned not to place undue reliance on such forward-looking statements and information, which are qualified in their entirety by this cautionary statement. All forward-looking statements and information made herein are based on our current expectations and we undertake no obligation to revise or update such forward- looking statements and information to reflect subsequent events or circumstances, except as required by law.

On Behalf of the Board of Directors
Dr. Mark Day, CEO

“Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.”

Company Contact
Graeme Dick
biOasis Technologies Inc.
info@bioasis.ca
1 (403) 561-8989

biOasis CEO Dr. Mark Day Releases Details of Corporate Plans in Message to Shareholders

Wednesday, June 14, 2017|0 Comments

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June 14, 2017, Vancouver, BC

BIOASIS TECHNOLOGIES INC. (OTCQB:BIOAF; TSX.V:BTI) Dr. Mark Day, chief executive officer, has issued a message to shareholders detailing plans for the advancement of the Transcend Platform and the company’s in-house programs.

To the Shareholders of biOasis Technologies Inc.:

As the new CEO of biOasis, I am delighted to send my first message to shareholders, especially at a time when there is such excitement in the neurosciences. Scientists are beginning to understand the surreal complexity of the central nervous system (CNS), how to explore further into its mysteries, to understand its workings, diagnose its diseases, and how to accurately monitor the progress of CNS diseases and the efficacy of the drugs that treat them.

I and my many friends and colleagues in the industry are moving ahead on many fronts. Celgene and Vertex have recently moved into the CNS arena under the guidance of two exceptional R&D leaders. In 2014 the Nobel Prize in Physiology or Medicine was awarded to a team that made breakthrough discoveries on spatial memory, discoveries that have informed my own work.

Several significant breakthroughs were made in the last year. The most exciting for me was with Alzheimer’s disease. Biogen demonstrated their aducanumab could slow the progression of Alzheimer’s disease in mild-to-moderate patients. This truly was a first and shows that when you prioritize science, you can yield truly astounding results.

And now, as CEO of biOasis, I find myself right in the middle of this new era in neuroscience with what I have previously called, “one of the most unique and promising blood-brain barrier technologies of our time.” Despite all the advances in neuroscience, the ability to transport drugs across the blood-brain barrier has remained elusive, something I believe biOasis and our Transcend Platform can address.

During the past few weeks, I have completed assessments of the Transcend Platform, the studies and data relating to the platform, the company’s Transcend patent portfolio and the two business models developed by the company. I have come away from this process more excited than ever. I believe the Transcend Platform, with its unique abilities, simplicity and comprehensive intellectual property (IP) protection, enables the two business models, and that the company should immediately move forward with them.

In the remainder of this first letter to shareholders, I will discuss the company’s internal clinical programs. In a future message, I will similarly discuss the company’s licensing model. I believe it is important for the pharmaceutical industry to keep pace with biOasis with respect to the delivery of drug candidates across the BBB and into the CNS. The Transcend licensing model will allow our future licensees to do that.

We Are a Science-Focused and Science-Driven Company.
Our focus is to do the right studies, at the right time, for the right reasons, a focus designed to bring success. We must avoid the mistake of rushing into clinical studies until we are certain we have the right endpoints. Otherwise we will succumb to the same issues that have led to the collapse of many biotech companies before us. Our studies and trials must have the right “go” or “no-go” endpoints.

The value in Transcend is the potential to turn non-brain-penetrant drugs into novel medical entities, to deliver them to the brain and to treat a range of disorders across oncology, lysosomal disorders and neurodegenerative diseases. A drug that did not treat the neurological aspects of a disease but can now be non-invasively delivered to the brain is not just a “bio-better,” it is a differentiated product.

In the immediate near term, our aim is to select, in a disciplined manner, the best assets to take into patients. This is not something to be undertaken without due consideration. We need to ensure the drugs have the following characteristics:

  • Target Engagement: The drug must reach its target in the brain (e.g., brain metastasis/glioblastoma) in sufficient quantities to be able to test the hypothesis in the clinic. Most drugs fail because they fail to get enough of the drug to the target.
  • Pharmacodynamic Activity: Once at its destination in the brain, the drug/target interaction should drive a biological consequence (e.g., in schizophrenia this could be the reduction of dopamine, a brain chemical that is excessive in the disease).
  • Patient Selection: We must ensure we have the right patient population to test.

Our plan is to utilize non-invasive, non-human primate (NHP) brain imaging to assess eight targets (across oncology, rare diseases and neurological indications) for their ability to get to the needed site of action in the brain. Only those targets showing actual target engagement will advance into phase 0 microdosing studies. This means we advance only those drugs where we see significant uptake in NHP imaging. The drugs with the best brain uptake will be prioritized for their use in human phase 0 studies.

Details of these studies will be released when our plans are completed. The NHP studies will not directly impact the previously discussed phase 0 clinical trial in oncology. We have already selected a manufacturer to produce the clinical-grade fusion proteins required for the study. The development of the cell line to produce the fusion protein and the manufacturing of the required quantity of the drug will take up to a year to complete.

It’s also essential to recognize one of the main receptors Transcend utilizes to trick the brain into opening the BBB is expressed in important regions of the brain, including areas critical to learning, memory, mood and impulsivity. This receptor is significantly expressed in glioblastomas and in key areas of the brain involved in a plethora of psychiatric and neurological diseases. I think these represent very intriguing targets for biOasis.

With respect to our in-house programs, it is essential for biOasis to have access to the best scientific advice available. To that end, we are currently creating a Scientific Advisory Committee with its members to be chosen from among the world’s top scientists. We are also assessing our internal expertise and management requirements. In the very near future, I expect to be making announcements about strategic appointments to address those requirements.

The biOasis in-house programs are a major undertaking. They are being developed in a robust scientific manner, with meaningful targets chosen to help ensure success. That success could produce ground-breaking results and could herald a broadly-recognized new era in neuroscience. I believe it’s possible, and that’s why I want to be right here at biOasis, and nowhere else.

In my previous roles in pharma, I have passionately driven research and development (R&D) and business development (BD) programs and I have succeeded in delivering new innovations to the R&D and BD processes. As CEO, I intend to bring the same dedication and vision to biOasis.

I want to thank the Executive Chairman, the Board of Directors and all our shareholders for this opportunity. Together we will accomplish great things and I look forward to working with you.

Sincerely,

Mark Day, Ph.D.
Chief Executive Officer
biOasis Technologies Inc.

About Transcend
Transcend is biOasis’ proprietary platform for the delivery of therapeutics across the blood-brain barrier to address unmet medical needs in the treatment of metastatic brain cancers as well as neurodegenerative and metabolic diseases. The delivery of therapeutics across the blood-brain barrier represents the single greatest challenge in treating neurological disorders. The ability to effectively and safely transverse the blood-brain barrier with the Transcend peptide carrier, MTfp, offers the opportunity for biOasis to deliver therapeutics into the brain at doses sufficient to have a therapeutic effect.

About biOasis
biOasis Technologies Inc. is a biopharmaceutical company headquartered in the Vancouver, Canada area, focused on overcoming the limitations of therapeutic drug delivery across the blood-brain barrier (BBB). The company is developing and commercializing a proprietary brain delivery technology to address unmet medical needs in the treatment of central nervous system disorders. biOasis trades on the OTCQB under the symbol “BIOAF” and on the TSX Venture Exchange under the symbol “BTI.” For more information about the company please visit www.bioasis.ca.

Forward Looking Statements
Certain statements in this press release contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 or forward-looking information under applicable Canadian securities legislation that may not be based on historical fact, including without limitation statements containing the words “believe”, “may”, “plan”, “will”, “estimate”, “continue”, “anticipate”, “intend”, “expect” and similar expressions. Such forward-looking statements or information involve known and unknown risks, uncertainties and other factors that may cause our actual results, events or developments, or industry results, to be materially different from any future results, events or developments express or implied by such forward-looking statements or information. Such factors include, among others, our stage of development, lack of any product revenues, additional capital requirements, risk associated with the completion of clinical trials and obtaining regulatory approval to market our products, the ability to protect our intellectual property, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing. Specifically, certain risks and uncertainties that could cause such actual events or results expressed or implied by such forward-looking statements and information to differ materially from any future events or results expressed or implied by such statements and information include, but are not limited to, the risks and uncertainties that: products that we develop may not succeed in preclinical or clinical trials, or future products in our targeted corporate objectives; our future operating results are uncertain and likely to fluctuate; we may not be able to raise additional capital; we may not be successful in establishing additional corporate collaborations or licensing arrangements; we may not be able to establish marketing and the costs of launching our products may be greater than anticipated; we have no experience in commercial manufacturing; we may face unknown risks related to intellectual property matters; we face increased competition from pharmaceutical and biotechnology companies; and other factors as described in detail in our filings with the Canadian securities regulatory authorities at www.sedar.com. Given these risks and uncertainties, you are cautioned not to place undue reliance on such forward-looking statements and information, which are qualified in their entirety by this cautionary statement. All forward-looking statements and information made herein are based on our current expectations and we undertake no obligation to revise or update such forward- looking statements and information to reflect subsequent events or circumstances, except as required by law.

On Behalf of the Board of Directors
Rob Hutchison, Chairman of The Board of Directors

“Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release”

Company Contact
Graeme Dick
biOasis Technologies Inc.
info@bioasis.ca
1- (403) 561-8989

biOasis to Present at The Global Chinese Financial Forum – Shanghai Conference 2017

Thursday, June 8, 2017|0 Comments

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June 8, 2017, Vancouver, BC

BIOASIS TECHNOLOGIES INC. (OTCQB:BIOAF; TSX.V:BTI) announced today that Dr. Mark Day, the chief executive officer of biOasis, will present at the Global Chinese Financial Forum (GCFF) – Shanghai Conference 2017, in Shanghai, China, on June 22, 2017. biOasis Board Chairman, Rob Hutchison, will attend the conference with Dr. Day.

Dr. Day’s presentation, “A Ground-Breaking Platform for the Delivery of Therapeutic Compounds Across the Blood-Brain Barrier,” will be attended by a wide assortment of private investors, life science companies and investment funds. The GCFF – Shanghai Conference 2017 will be held concurrently with China’s largest pharma-focused event, the CPhI China Conference.

“The Chinese pharmaceutical industry is one of the largest in the world with double-digit growth and exceptional opportunities for biOasis,” said Dr. Mark Day, CEO, biOasis. “The GCFF – Shanghai Conference 2017 offers biOasis the opportunity to introduce our Transcend Platform to executives and scientists from many of China’s largest life science companies and to begin building alliances throughout Asia.”

“On a personal note, the conference is my first opportunity to publicly express my excitement about biOasis and to discuss our strategies for the Transcend Platform going forward,” said Dr. Day. “I have described Transcend as one of the most unique and promising blood-brain barrier technologies of our time. I look forward to meeting my industry colleagues and establishing new ones, placing biOasis in the mix of growth opportunities the Chinese pharmaceutical industry can offer us.”

About Transcend
Transcend is biOasis’ proprietary platform for the delivery of therapeutics across the blood-brain barrier to address unmet medical needs in the treatment of metastatic brain cancers as well as neurodegenerative and metabolic diseases. The delivery of therapeutics across the blood-brain barrier represents the single greatest challenge in treating neurological disorders. The ability to effectively and safely transverse the blood-brain barrier with the Transcend peptide carrier, MTfp, offers the opportunity for biOasis to deliver therapeutics into the brain at doses sufficient to have a therapeutic effect.

About biOasis
biOasis Technologies Inc. is a biopharmaceutical company headquartered in the Vancouver, Canada area, focused on overcoming the limitations of therapeutic drug delivery across the blood-brain barrier (BBB). The company is developing and commercializing a proprietary brain delivery technology to address unmet medical needs in the treatment of central nervous system disorders. biOasis trades on the OTCQB under the symbol “BIOAF” and on the TSX Venture Exchange under the symbol “BTI.” For more information about the company please visit www.bioasis.ca.

Forward Looking Statements
Certain statements in this press release contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 or forward-looking information under applicable Canadian securities legislation that may not be based on historical fact, including without limitation statements containing the words “believe”, “may”, “plan”, “will”, “estimate”, “continue”, “anticipate”, “intend”, “expect” and similar expressions. Such forward-looking statements or information involve known and unknown risks, uncertainties and other factors that may cause our actual results, events or developments, or industry results, to be materially different from any future results, events or developments express or implied by such forward-looking statements or information. Such factors include, among others, our stage of development, lack of any product revenues, additional capital requirements, risk associated with the completion of clinical trials and obtaining regulatory approval to market our products, the ability to protect our intellectual property, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing. Specifically, certain risks and uncertainties that could cause such actual events or results expressed or implied by such forward-looking statements and information to differ materially from any future events or results expressed or implied by such statements and information include, but are not limited to, the risks and uncertainties that: products that we develop may not succeed in preclinical or clinical trials, or future products in our targeted corporate objectives; our future operating results are uncertain and likely to fluctuate; we may not be able to raise additional capital; we may not be successful in establishing additional corporate collaborations or licensing arrangements; we may not be able to establish marketing and the costs of launching our products may be greater than anticipated; we have no experience in commercial manufacturing; we may face unknown risks related to intellectual property matters; we face increased competition from pharmaceutical and biotechnology companies; and other factors as described in detail in our filings with the Canadian securities regulatory authorities at www.sedar.com. Given these risks and uncertainties, you are cautioned not to place undue reliance on such forward-looking statements and information, which are qualified in their entirety by this cautionary statement. All forward-looking statements and information made herein are based on our current expectations and we undertake no obligation to revise or update such forward- looking statements and information to reflect subsequent events or circumstances, except as required by law.

On Behalf of the Board of Directors
Rob Hutchison, Chairman of The Board of Directors

“Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release”

Company Contact
Graeme Dick
biOasis Technologies Inc.
info@bioasis.ca
1- (403) 561-8989

biOasis to Present at the 16th International Postgraduate Course on Lysosomal Storage Disorders

Sunday, June 4, 2017|0 Comments

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June 4, 2017, Vancouver, BC

BIOASIS TECHNOLOGIES INC. (OTCQB:BIOAF; TSX.V:BTI) announced today that Dr. Mark Day, chief executive officer, will present at the 16th International Postgraduate Course on Lysosomal Storage Disorders, in Nierstein (Mainz), Germany on June 07 – 10, 2017.

Dr. Day’s presentation, “Improving the Probability of Success in CNS Drug Discovery and Development: A Case Study,” targets issues relating to therapies to treat the central nervous system (CNS). The workshop is academic in nature and will be attended by scientists from companies and institutions that are focused on lysosomal storage diseases.

Lysosomal storage diseases (LSDs) are a group of inherited metabolic disorders, some of which cause significant impairments in neurological function. The disorders are caused by dysfunctional or missing enzymes that are required for the processing and removal of unwanted cellular materials.

Several LSDs can be treated with enzyme replacement therapy, the intravenous infusion of a solution containing the missing enzyme. However, the blood-brain barrier blocks most therapeutics, including enzymes, from entering the CNS in sufficient quantities to effectively treat neurological disorders. The inability of most therapeutics to enter the CNS has resulted in areas of great unmet medical need.

“Our Transcend peptide technology specifically addresses the issue of delivery of therapeutics across the blood-brain barrier,” said Dr. Mark Day, CEO of biOasis. “From the preclinical data we’ve generated to date, we are excited to move several targets, including enzymes, antibodies and small molecules, through de-risking imaging studies and into clinical assessment. This workshop allows me to meet with many of the stakeholders in this very key market for us.”

About Transcend
Transcend is biOasis’ proprietary platform for the delivery of therapeutics across the blood-brain barrier to address unmet medical needs in the treatment of metastatic brain cancers as well as neurodegenerative and metabolic diseases. The delivery of therapeutics across the blood-brain barrier represents the single greatest challenge in treating neurological disorders. The ability to effectively and safely transverse the blood-brain barrier with the Transcend peptide carrier, MTfp, offers the opportunity for biOasis to deliver therapeutics into the brain at doses sufficient to have a therapeutic effect.

About biOasis
biOasis Technologies Inc. is a biopharmaceutical company headquartered in the Vancouver, Canada area, focused on overcoming the limitations of therapeutic drug delivery across the brain-blood barrier. The company is developing and commercializing a proprietary brain delivery technology to address unmet medical needs in the treatment of central nervous system disorders. biOasis trades on the OTCQB under the symbol “BIOAF” and on the TSX Venture Exchange under the symbol “BTI.” For more information about the company, please visit www.bioasis.ca.

Forward Looking Statements
Certain statements in this press release contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 or forward-looking information under applicable Canadian securities legislation that may not be based on historical fact, including without limitation statements containing the words “believe”, “may”, “plan”, “will”, “estimate”, “continue”, “anticipate”, “intend”, “expect” and similar expressions. Such forward-looking statements or information involve known and unknown risks, uncertainties and other factors that may cause our actual results, events or developments, or industry results, to be materially different from any future results, events or developments express or implied by such forward-looking statements or information. Such factors include, among others, our stage of development, lack of any product revenues, additional capital requirements, risk associated with the completion of clinical trials and obtaining regulatory approval to market our products, the ability to protect our intellectual property, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing. Specifically, certain risks and uncertainties that could cause such actual events or results expressed or implied by such forward-looking statements and information to differ materially from any future events or results expressed or implied by such statements and information include, but are not limited to, the risks and uncertainties that: products that we develop may not succeed in preclinical or clinical trials, or future products in our targeted corporate objectives; our future operating results are uncertain and likely to fluctuate; we may not be able to raise additional capital; we may not be successful in establishing additional corporate collaborations or licensing arrangements; we may not be able to establish marketing and the costs of launching our products may be greater than anticipated; we have no experience in commercial manufacturing; we may face unknown risks related to intellectual property matters; we face increased competition from pharmaceutical and biotechnology companies; and other factors as described in detail in our filings with the Canadian securities regulatory authorities at www.sedar.com. Given these risks and uncertainties, you are cautioned not to place undue reliance on such forward-looking statements and information, which are qualified in their entirety by this cautionary statement. All forward-looking statements and information made herein are based on our current expectations and we undertake no obligation to revise or update such forward- looking statements and information to reflect subsequent events or circumstances, except as required by law.

On Behalf of the Board of Directors
Dr. Mark Day, CEO

“Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release”

Company Contact
Graeme Dick
biOasis Technologies Inc.
info@bioasis.ca
1- (403) 561-8989

biOasis Announces the Engagement of Mackie Research to Provide Market Making Services

Tuesday, May 16, 2017|0 Comments

THIS NEWS RELEASE IS NOT FOR DISSEMINATION IN THE UNITED STATES

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May 16th, 2017, Vancouver, BC

BIOASIS TECHNOLOGIES INC. (OTCQB:BIOAF; TSX.V:BTI) (the “Company”), is pleased to announce that, subject to regulatory approval, it has retained Mackie Research Capital Corporation (“Mackie Research”) to initiate its market making service to provide market making services to the Company in compliance with the policies and guidelines of the TSX Venture Exchange and other applicable legislation.
Mackie Research will trade shares of the Company on the TSXV for the purposes of maintaining a reasonable market and improving the liquidity of the Company’s common shares. The agreement between Mackie Research and the Company is for a minimum four months and the Company has agreed to pay Mackie Research $10,000 per month for the initial two months, increases to $15,000 for the final two months. After the initial period, the engagement may be terminated by either party with written notice of 30 days. The Company and Mackie Research act at arm’s length, but Mackie Research may provide investment banking services to the Company and Mackie Research and/or its clients may have an interest, directly or indirectly, in the securities of the Company. The agreement is principally for the purposes of maintaining market stability and liquidity for the Company’s common shares and is not a formal market making agreement. The finances and the shares required for the market-making service are provided by Mackie Research. There are no performance factors contained in the agreement between Mackie Research and the Company and Mackie Research will not receive any shares or options from the Company as compensation for services it will render.

About Mackie Research Capital Corporation
Mackie Research is one of Canada’s largest independent full service investment firms, and proudly traces its roots back to 1921. Mackie Research is privately owned by many of its 300 employees. As a fully integrated national investment dealer, Mackie Research offers a full complement of capital markets and wealth management services to private clients, institutions and growth companies.

About biOasis
biOasis Technologies Inc. is a biopharmaceutical company headquartered in the Vancouver, Canada area, focused on overcoming the limitations of therapeutic drug delivery across the BBB. The company is developing and commercializing a proprietary brain delivery technology to address unmet medical needs in the treatment of central nervous system disorders. biOasis trades on the OTCQB under the symbol “BIOAF” and on the TSX Venture Exchange under the symbol “BTI”. For more information about the company please visit www.bioasis.ca.

Forward Looking Statements
Certain statements in this press release contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 or forward-looking information under applicable Canadian securities legislation that may not be based on historical fact, including without limitation statements containing the words “believe”, “may”, “plan”, “will”, “estimate”, “continue”, “anticipate”, “intend”, “expect” and similar expressions. Such forward-looking statements or information involve known and unknown risks, uncertainties and other factors that may cause our actual results, events or developments, or industry results, to be materially different from any future results, events or developments express or implied by such forward-looking statements or information. Such factors include, among others, our stage of development, lack of any product revenues, additional capital requirements, risk associated with the completion of clinical trials and obtaining regulatory approval to market our products, the ability to protect our intellectual property, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing. Specifically, certain risks and uncertainties that could cause such actual events or results expressed or implied by such forward-looking statements and information to differ materially from any future events or results expressed or implied by such statements and information include, but are not limited to, the risks and uncertainties that: products that we develop may not succeed in preclinical or clinical trials, or future products in our targeted corporate objectives; our future operating results are uncertain and likely to fluctuate; we may not be able to raise additional capital; we may not be successful in establishing additional corporate collaborations or licensing arrangements; we may not be able to establish marketing and the costs of launching our products may be greater than anticipated; we have no experience in commercial manufacturing; we may face unknown risks related to intellectual property matters; we face increased competition from pharmaceutical and biotechnology companies; and other factors as described in detail in our filings with the Canadian securities regulatory authorities at www.sedar.com. Given these risks and uncertainties, you are cautioned not to place undue reliance on such forward-looking statements and information, which are qualified in their entirety by this cautionary statement. All forward-looking statements and information made herein are based on our current expectations and we undertake no obligation to revise or update such forward- looking statements and information to reflect subsequent events or circumstances, except as required by law.

On Behalf of the Board of Directors
Rob Hutchison, Executive Chairman of the Board of Directors

“Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release”

Company Contact
Graeme Dick
biOasis Technologies Inc.
info@bioasis.ca
1-403-561-8989

biOasis Appoints Mark Day, Ph.D., as Chief Executive Officer and Director

Tuesday, April 25, 2017|0 Comments

THIS NEWS RELEASE IS NOT FOR DISSEMINATION IN THE UNITED STATES

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April 24th, 2017, Vancouver, BC

BIOASIS TECHNOLOGIES INC. (OTCQB:BIOAF; TSX.V:BTI) (the “Company”) has appointed Mark Day, Ph.D., as President and Chief Executive Officer of the Company, effective immediately. Dr. Day succeeds Mr. Rob Hutchison who will become Executive Chairman of the Board of Directors of the Company. Dr. Day will also serve on the biOasis Board of Directors.

Dr. Day most recently served as Head, CNS Virtual Discovery at Purdue Pharma. Prior to joining Purdue, Dr. Day served as Executive Director, Head of External Research & Scouting at Alexion Pharmaceuticals, Inc. Dr. Day also serves as Adjunct Associate Professor (Neuroscience) at Yale University.

Dr. Day is widely recognized for his expertise and success in the recognition, evaluation and development of pipeline acquisition and collaboration targets across several therapeutic areas, including neurotherapeutics and rare diseases. In pursuit of business development opportunities, Dr. Day has evaluated over 300 programs, resulting in a uniquely broad knowledge of the pharmaceutical industry and its opportunities. In the process, he has developed business and personal relationships with many of the industry’s leading executives.

Demonstrating corporate leadership, Dr. Day has developed business plans for Alexion, Purdue, Wyeth and Bristol-Myers Squibb in multiple functional areas ranging from the development of external research discovery engines and global scouting strategies to the creation of internal venture/investment funds. To facilitate the rapid evaluation of pipeline acquisition and collaboration opportunities, and to lower the costs in time and funding of evaluative processes, Dr. Day has developed strategies that can shorten evaluation periods by several months, leading to early decisions regarding the advancement or early termination of the evaluative processes. Dr. Day has presented his evaluations and formal recommendations at the highest corporate levels. He has also participated in the resulting deal negotiations, leading to several high-profile acquisitions and collaborations.

Dr. Day holds a Ph.D., Neuroscience, from Cardiff University in Wales. He completed Post-Doctoral work in Systems Level Neuroscience at The University of Edinburgh where he investigated the effects of glutamate-receptor subtypes on encoding, memory consolidation and retrieval of paired-associate learning (PAL). Over his academic and industry career, Dr. Day has published over 60 peer-reviewed scientific papers in world-leading journals (e.g. Nature, Science, Proceedings of the Royal Society, Nature Neuroscience). He has managed research teams and has created and chaired a governance team for the management of a $30M R&D budget. He has also established and managed R&D alliances and collaborations with contract research organizations, academic laboratories and foundations in the USA, European Union, Australia and Asia.

Mr. Rob Hutchison, Chairman of the Board of Directors, stated, “The Board of Directors and I are very pleased to welcome Dr. Mark Day to biOasis. Mark has established himself as a leader in the pharmaceutical industry, both as a business development executive and as a neuroscientist. He has a proven ability to discover and evaluate neurotherapeutic pipeline opportunities on both scientific and business levels, to present compelling proposals to potential partners, to manage teams and to negotiate deals. I want to personally welcome Mark and I’m looking forward to working with him.”

biOasis CEO, Dr. Mark Day, commented, “I consider the biOasis Transcend Platform to be one of the most unique and promising blood-brain barrier technologies of our time. Ensuring that experimental medicines are able to reach their targets in the brain has been shown to improve their probability of success. The development of neurotherapeutics has always been limited by the inability to get drugs across the blood-brain barrier. In fact, it’s been nearly impossible to develop drugs that have both the right chemical structures to target CNS diseases, and to have, at the same time, structures that allow them to cross the blood-brain barrier. The two objectives are often completely incompatible.”

“The Transcend Platform may finally give the pharmaceutical industry the ability to design neurotherapeutics with the knowledge that, no matter a drug’s chemical structure, the Transcend peptide can likely be used get it across the blood-brain barrier in a very natural and cost-effective manner. The unmet medical needs for this are huge.”

“I want to thank the biOasis Board of Directors and Rob Hutchison for this opportunity. I’m looking forward to leading the commercial and scientific advancement of the Transcend Platform for the benefit of patients, our pharmaceutical industry partners and licensees, and for biOasis shareholders. I’m looking forward to seeing where this can go.”

About Transcendpep
Transcend is biOasis’ proprietary platform for the delivery of therapeutics across the blood-brain barrier to address unmet medical needs in the treatment of metastatic brain cancers as well as neurodegenerative and metabolic diseases. The delivery of therapeutics across the blood-brain barrier represents the single greatest challenge in treating neurological disorders. The ability to effectively and safely transverse the blood-brain barrier with the Transcend peptide carrier, MTfp, offers the opportunity for biOasis to deliver therapeutics into the brain at doses sufficient to have a therapeutic effect.

About biOasis
biOasis Technologies Inc. is a biopharmaceutical company headquartered in the Vancouver, Canada area, focused on overcoming the limitations of therapeutic drug delivery across the BBB. The Company is developing and commercializing a proprietary brain delivery technology to address unmet medical needs in the treatment of central nervous system disorders. For more information about the company please visit www.bioasis.ca.

Forward Looking Statements
Certain statements in this press release contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 or forward-looking information under applicable Canadian securities legislation that may not be based on historical fact, including without limitation statements containing the words “believe”, “may”, “plan”, “will”, “estimate”, “continue”, “anticipate”, “intend”, “expect” and similar expressions. Such forward-looking statements or information involve known and unknown risks, uncertainties and other factors that may cause our actual results, events or developments, or industry results, to be materially different from any future results, events or developments express or implied by such forward-looking statements or information. Such factors include, among others, our stage of development, lack of any product revenues, additional capital requirements, risk associated with the completion of clinical trials and obtaining regulatory approval to market our products, the ability to protect our intellectual property, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing. Specifically, certain risks and uncertainties that could cause such actual events or results expressed or implied by such forward-looking statements and information to differ materially from any future events or results expressed or implied by such statements and information include, but are not limited to, the risks and uncertainties that: products that we develop may not succeed in preclinical or clinical trials, or future products in our targeted corporate objectives; our future operating results are uncertain and likely to fluctuate; we may not be able to raise additional capital; we may not be successful in establishing additional corporate collaborations or licensing arrangements; we may not be able to establish marketing and the costs of launching our products may be greater than anticipated; we have no experience in commercial manufacturing; we may face unknown risks related to intellectual property matters; we face increased competition from pharmaceutical and biotechnology companies; and other factors as described in detail in our filings with the Canadian securities regulatory authorities at www.sedar.com. Given these risks and uncertainties, you are cautioned not to place undue reliance on such forward-looking statements and information, which are qualified in their entirety by this cautionary statement. All forward-looking statements and information made herein are based on our current expectations and we undertake no obligation to revise or update such forward- looking statements and information to reflect subsequent events or circumstances, except as required by law.

On Behalf of the Board of Directors
Rob Hutchison, Executive Chairman of the Board of Directors

“Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release”

Company Contact
Rob Hutchison
biOasis Technologies Inc.
info@bioasis.ca
1-604-644-1232

biOasis Announces Investor Relations Service Agreement

Tuesday, April 25, 2017|0 Comments

THIS NEWS RELEASE IS NOT FOR DISSEMINATION IN THE UNITED STATES

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April 24, 2017, Vancouver, BC

BIOASIS TECHNOLOGIES INC. (OTCQB:BIOAF; TSX.V:BTI) (the “Company”) The Company announces that it has entered into an investor relations agreement (“Agreement”) with 551943 Alberta Ltd., operating as Colwell Capital Corp (“Colwell”), for a maximum term of twelve months commencing April 24, 2017. The Company will pay Colwell $4,000 per month and will grant Colwell 175,000 stock options. The Agreement and the option grant are subject to regulatory approval.

Rob Hutchison, Executive Chairman commented, “We welcome Colwell on board. As the Company, under new senior management leadership, enters this exciting phase, a formal investor communications program is must. We fully expect Colwell to provide that conduit to our shareholders.”

About Transcendpep
Transcend is biOasis’ proprietary platform for the delivery of therapeutics across the blood-brain barrier to address unmet medical needs in the treatment of metastatic brain cancers as well as neurodegenerative and metabolic diseases. The delivery of therapeutics across the blood-brain barrier represents the single greatest challenge in treating neurological disorders. The ability to effectively and safely transverse the blood-brain barrier with the Transcend peptide carrier, MTfp, offers the opportunity for biOasis to deliver therapeutics into the brain at doses sufficient to have a therapeutic effect.

About biOasis
biOasis Technologies Inc. is a biopharmaceutical company headquartered in the Vancouver, Canada area, focused on overcoming the limitations of therapeutic drug delivery across the BBB. The Company is developing and commercializing a proprietary brain delivery technology to address unmet medical needs in the treatment of central nervous system disorders. For more information about the company please visit www.bioasis.ca.

Forward Looking Statements
Certain statements in this press release contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 or forward-looking information under applicable Canadian securities legislation that may not be based on historical fact, including without limitation statements containing the words “believe”, “may”, “plan”, “will”, “estimate”, “continue”, “anticipate”, “intend”, “expect” and similar expressions. Such forward-looking statements or information involve known and unknown risks, uncertainties and other factors that may cause our actual results, events or developments, or industry results, to be materially different from any future results, events or developments express or implied by such forward-looking statements or information. Such factors include, among others, our stage of development, lack of any product revenues, additional capital requirements, risk associated with the completion of clinical trials and obtaining regulatory approval to market our products, the ability to protect our intellectual property, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing. Specifically, certain risks and uncertainties that could cause such actual events or results expressed or implied by such forward-looking statements and information to differ materially from any future events or results expressed or implied by such statements and information include, but are not limited to, the risks and uncertainties that: products that we develop may not succeed in preclinical or clinical trials, or future products in our targeted corporate objectives; our future operating results are uncertain and likely to fluctuate; we may not be able to raise additional capital; we may not be successful in establishing additional corporate collaborations or licensing arrangements; we may not be able to establish marketing and the costs of launching our products may be greater than anticipated; we have no experience in commercial manufacturing; we may face unknown risks related to intellectual property matters; we face increased competition from pharmaceutical and biotechnology companies; and other factors as described in detail in our filings with the Canadian securities regulatory authorities at www.sedar.com. Given these risks and uncertainties, you are cautioned not to place undue reliance on such forward-looking statements and information, which are qualified in their entirety by this cautionary statement. All forward-looking statements and information made herein are based on our current expectations and we undertake no obligation to revise or update such forward- looking statements and information to reflect subsequent events or circumstances, except as required by law.

On Behalf of the Board of Directors
Rob Hutchison, Executive Chairman of the Board of Directors

“Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release”

Company Contact
Graeme Dick
Investor Relations Contact
info@bioasis.ca
1-403-561-8989

BIOASIS ANNOUNCES GRANT OF STOCK OPTIONS AND RESTRICTED STOCK UNITS

Tuesday, April 25, 2017|0 Comments

THIS NEWS RELEASE IS NOT FOR DISSEMINATION IN THE UNITED STATES

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April 24, 2017, Vancouver, BC

BIOASIS TECHNOLOGIES INC. (OTCQB:BIOAF; TSX.V:BTI) (the “Company”) is pleased to announce that pursuant to the terms of its stock option plan (the “Option Plan”) and restricted stock units plan (the “RSU Plan”), the Company has granted a total of 2,377,478 stock options and 225,000 Restricted Share Units (RSUs) to its officers, employees, consultants and members of the Board of Directors. The stock options are exercisable at a price of $0.80 per share for a period of five years from the date of grant.

Pursuant to the investor relations agreement between the Company and 551943 Alberta Ltd. (operating as Colwell Capital Corp) (“Colwell”), announced on April 24, 2017, the Company has granted a total of 175,000 stock options to Colwell. These stock options are exercisable at a price of $0.80 per share for a period of five years from the date of grant. The IR options will vest quarterly over twelve months, with 43,750 stock options vesting on July 24, 2017, 43,750 vesting on October 24, 2017, 43,750 vesting on January 24, 2018 and 43,750 vesting on April 24, 2018.

The stock options and RSUs follow the guidelines as set out in the Company’s Option Plan and RSU Plan and as set by the TSX Venture Policies. The RSU grants are subject to the approval of the TSX Venture Exchange.

About Transcendpep
Transcend is biOasis’ proprietary platform for the delivery of therapeutics across the blood-brain barrier to address unmet medical needs in the treatment of metastatic brain cancers as well as neurodegenerative and metabolic diseases. The delivery of therapeutics across the blood-brain barrier represents the single greatest challenge in treating neurological disorders. The ability to effectively and safely transverse the blood-brain barrier with the Transcend peptide carrier, MTfp, offers the opportunity for biOasis to deliver therapeutics into the brain at doses sufficient to have a therapeutic effect.

About biOasis
biOasis Technologies Inc. is a biopharmaceutical company headquartered in the Vancouver, Canada area, focused on overcoming the limitations of therapeutic drug delivery across the BBB. The Company is developing and commercializing a proprietary brain delivery technology to address unmet medical needs in the treatment of central nervous system disorders. For more information about the company please visit www.bioasis.ca.

Forward Looking Statements
Certain statements in this press release contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 or forward-looking information under applicable Canadian securities legislation that may not be based on historical fact, including without limitation statements containing the words “believe”, “may”, “plan”, “will”, “estimate”, “continue”, “anticipate”, “intend”, “expect” and similar expressions. Such forward-looking statements or information involve known and unknown risks, uncertainties and other factors that may cause our actual results, events or developments, or industry results, to be materially different from any future results, events or developments express or implied by such forward-looking statements or information. Such factors include, among others, our stage of development, lack of any product revenues, additional capital requirements, risk associated with the completion of clinical trials and obtaining regulatory approval to market our products, the ability to protect our intellectual property, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing. Specifically, certain risks and uncertainties that could cause such actual events or results expressed or implied by such forward-looking statements and information to differ materially from any future events or results expressed or implied by such statements and information include, but are not limited to, the risks and uncertainties that: products that we develop may not succeed in preclinical or clinical trials, or future products in our targeted corporate objectives; our future operating results are uncertain and likely to fluctuate; we may not be able to raise additional capital; we may not be successful in establishing additional corporate collaborations or licensing arrangements; we may not be able to establish marketing and the costs of launching our products may be greater than anticipated; we have no experience in commercial manufacturing; we may face unknown risks related to intellectual property matters; we face increased competition from pharmaceutical and biotechnology companies; and other factors as described in detail in our filings with the Canadian securities regulatory authorities at www.sedar.com. Given these risks and uncertainties, you are cautioned not to place undue reliance on such forward-looking statements and information, which are qualified in their entirety by this cautionary statement. All forward-looking statements and information made herein are based on our current expectations and we undertake no obligation to revise or update such forward- looking statements and information to reflect subsequent events or circumstances, except as required by law.

On Behalf of the Board of Directors
Rob Hutchison, Executive Chairman of the Board of Directors

“Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release”

Company Contact
Graeme Dick
Investor Relations Contact
info@bioasis.ca
1-403-561-8989

When Transcend was conjugated with Trastuzumab it was shown in vivo to deliver Trastuzumab across the BBB and into the brain.
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Antibodies directed at Aβ could offer therapeutic opportunities for reducing amyloid plaques in the brain for a potential treatment in Alzheimer’s disease.
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Lysosomal storage diseases (“LSD”) are rare inherited metabolic diseases caused by a defective gene that result in an enzyme deficiency in lysosome cellular structures.
Read more…

Small-Interfering RNA (siRNA) is a gene silencing technology which can be used to reduce the expression (commonly called a “knock-down”) of specific disease causing genes.
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